Cancer is fundamentally difficult to cure because of the diversity in tumor microenvironments. Hypoxia, or the lack of sufficient oxygen in the microenvironment, allows cancer cells to become heterogenous through epigenetic adaptation. Heterogeneity in cancer cells...
The 2019 Nobel Prize in Physiology or Medicine was awarded jointly to William G. Kaelin Jr., Sir Peter J. Ratcliffe and Gregg L. Semenza for their discoveries of how cells sense and adapt to oxygen availability by using specific molecules that regulate the activity...
Epilepsy is one of the most prevalent neurological conditions found in approximately 50 million people worldwide. Epilepsy occurs throughout the age-span and is often characterized by spontaneous non-provoked seizures. Currently third generation antiepileptic...