Written by Angelo

Categories: supplements | Healthcare

April 26 2023

This fresh study1 dismantles once and for all the anti-scientific hoax of the Coimbra method and all the protocols that provide for more or less savage integration of vitamin D to suppress the symptoms of inflammatory and "autoimmune" diseases.

Researchers evaluated postural control and cognitive function in patients with relapsing-remitting multiple sclerosis (RRMS), the most common form2. About 85% of diagnosed people initially have this form, characterized by acute episodes of illness ('poussè' or 'relapses') alternating with periods of complete or partial well-being ('remissions'). The RR form can also be distinguished as active (presence of relapses and/or evidence of disease activity on MRI) or inactive, as well as worsening (confirmed increase in disability for a specified period of time after a relapse) or without worsening .

Poor postural control and cognitive dysfunction are well-established complications of RRMS, with no effective remedy yet. The latest research has sought to evaluate the potential independent immune-modulating effects of vitamin D3 and ultraviolet radiation in disease management.

The researchers involved in this study aimed to investigate the efficacy of broadband ultraviolet B radiation (UVBR) versus a moderate loading dose of vitamin D3 supplementation in improving postural control and cognitive functions.

The patients were randomized into two groups: The UVBR group involved 24 patients, who received sessions for 4 weeks, while the Vitamin D3 group involved 23 patients, who took a supplement for (50 000 IU/week) 12 weeks.

Both therapeutic programs were statistically equal in improving postural control and cognitive functions.

However, clinically, UVBR therapy was more cost-effective due to the shorter treatment time and higher rate of change for all measures tested.

Here then comes the objection of the doctor Coimbra...”but in any case the integration is also effective, and then they integrated very little… I would have given 50 units per minute shot directly into a drip…”

– Apart from the fact that phototherapy gives faster, better and cheaper results…

– Apart from the fact that it allows the production of vitamin D in a self-regulating way avoiding unnecessary intoxication… During exposure to sunlight, after previtamin D3 has been produced, it absorbs solar UVB radiation and isomerizes into two main photoproducts, lumisterol3 and tachysterol3.
Therefore, when the skin is exposed to sunlight, it can only convert about 15% of 7-dehydrocholesterol to previtamin D3. Each additional exposure results in a photoequilibrium in which previtamin D3 is converted to lumisterol3 and tachysterol3, or converted back to 7-DHC. Furthermore, when vitamin D3 is produced from previtamin D3 in the skin, it is converted into various suprasterols and 5,6-trans-vitamin D3 when it is exposed to solar UVB radiation by absorbing it. Furthermore, previtamin D3 can be converted into various toxisterols. Therefore, no matter how much sun you are exposed to, vitamin D poisoning will never occur, because any excess previtamin D3 and vitamin D3 is photodegraded into products with no calcium activity.
Additionally, the plethora of metabolites that are produced solely through exposure to UVB radiation are all biologically active and are not produced with supplementation.

In short, exposure to the sun is like pork… Nothing is thrown away!

In fact, this myriad of photoproducts exhibit numerous biological effects, such as regulating the growth of epidermal cells and reducing the risk of skin cancer. Lumisterol3, when converted to 1,25-dihydroxysterol3, may in fact have anticancer effects. Some suprasterols also have antiproliferative activity in cultured human keratinocytes. Thus, sensitive sun exposure to produce previtamin D3, vitamin D3 and its photoproducts, can have many additional benefits over simply taking a vitamin D3 supplement or ingesting vitamin D3 from dietary sources.

– Apart from the fact that thanks to phototherapy the sulphate form is produced, the most biologically active4…

Many studies show that vitamin D supplementation cannot reproduce the benefits of sunlight. Additionally, excessive supplementation can aggravate systemic sulfate deficiency, which leads to a buildup of calcium in the arteries.
The synthesis of sulphates in the skin captures solar energy. Adequate sunlight exposure for both skin and eyes is critical to our long-term health.
Among other functions, sulphate supports blood vessel health, nutrition “electric” body and the distribution system of important molecules such as cholesterol, vitamin D, dopamine and melatonin.
Sunlight has been shown to protect against cancer, heart disease, high blood pressure and bone fractures.

In the skin, sulfate is conjugated with both vitamin D and cholesterol, making the otherwise water-insoluble sulfate molecules water-soluble. This greatly facilitates their transport in the blood, because they no longer have to be enclosed within lipid particles such as high-density lipoproteins (HDL) and low-density lipoproteins (LDL). Exposure to sunlight therefore produces cholesterol and vitamin D in the sulphate form, with all the resulting benefits.

The benefits of exposure to sunlight (and using devices that use its most biologically active wavelengths), therefore, go far beyond vitamin D.

Apart from all this, which is already enough and more to celebrate the funeral of the Coimbra method and of all the protocols that provide for a more or less wild vitamin D integration ... the mechanisms underlying the improvements in multiple sclerosis are different.

• With integration, the symptoms go out, i.e. the "fuses" of the warning lights on the dashboard of the car are detached, but unfortunately if the engine problems are not addressed, sooner or later “you will stand”. The same thing happens with the disease: only the manifestations go out, i.e. the natural reactions that warn us that something is wrong, while the pathology advances inexorably and silently.

• With exposure to UVB radiation, other virtuous mechanisms are established which are independent of vitamin D and which go to the roots of the pathological process, instead of simply extinguishing the symptoms.

This has already been well explained in other studies, which we had already discussed in this blog article:


Here are the highlights to connect the dots:

…it was found that “Vitamin D deficiency has a protective effect on experimental autoimmune encephalomyelitis, a result diametrically opposed to the original hypothesis”.

What in these models has been able to put the disease into remission is hypercalcemia, caused by an excess of 1,25(OH)2D3 (recall that the ratio between the "active" and "deposit" forms depends by the inflammatory processes taking place in the body5), although some studies have demonstrated a correlation between high levels of calcium and the severity of the disease, suggesting a probable biphasic response deriving from mechanisms related to the immune system.

So, the "improvement" temporary symptoms is linked to a serious long-term risk, with soft tissue calcification, risk of osteoporosis and ultimately irreversible organ damage.

Instead, narrowband UVB phototherapy (300-315 nm - the one used by phototherapy devices ELIOSLAMP) is able to prevent and suppress autoimmune encephalomyelitis in experimental models in the face of modest changes in 25(OH)D3 levels, while (hear, hear!), 1,25(OH)2D3 even counteracts the efficacy of UV in the suppression of the disease (again due to the link with inflammatory processes).

Of course, the key is always "normalize" and balance the levels rather than suppress or cause X or Y to be produced, which is just what UVB radiation does.

The 9 trial came using mice suppressed of the Sc5d enzyme, unable to produce 7-DHC, mice unable to produce 1,25(OH)2D3 (Cypi27B1), or mice subjected to VDR inhibition.
The results show unequivocally that neither vitamin D metabolites nor VDRs are required for the suppression of UV-operated autoimmune encephalomyelitis.

The UV radiation, under which we have evolved for millions and millions of years, modulates the "immune system" by many vitamin D-independent mechanisms.

Instead of using the definition "immune modulation", based on the latest evidence in our possession, it is better to say that UVB radiation operates a real redox6 balance, the only fundamental parameter that represents the crossroads between health and disease.

Once the redox reactions are in place, health is assured.

Leading researchers in the field, such as HF DeLuca, argue that based on their models of experimental autoimmune encephalomyelitis, multiple sclerosis cannot be treated with vitamin D; indeed, their models suggest that such therapies are even contraindicated7.

We are truly sorry for the doctors who believed this umpteenth "panacea", but we feel even more sorry for their patients, deluded and intoxicated! So, in the end, the former take selfies in luxury resorts, while the latter have to deal not only with their pathology that will never "heal", but also with the potential harmful medium-long term effects caused by the 'integration.

However, it doesn't take a genius to understand that according to the rule of evolutionary mismatches, any approach that goes beyond and deviates from our evolutionary path in Nature will sooner or later present its salty bill.

UVB radiation, on the other hand, whether it comes from a lamp or whether it comes from the sun, is always the same. These are electromagnetic waves/photons…


Do you think that the study was done using very coarse phototherapy lamps with an inadequate broadband UVB technology.
Our lamps not only have the top of PHILIPS narrowband UVB technology but they also have a particular patent that "contaminates" the narrowband UVB with a broadband UVA that synergizes and makes our lamps the most effective in the world in their kind.











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